AquaFunc Public
Integrated knowledge on functional genomics in sustainable aquaculture

Project: Bivalvegene (Funded by MEC of Spain)


Project website :

Partners of the project :
Name Email Institutional homepage
Dr Beatriz Novoa virus(at)iim.csic.es


Links to the .ppt from Faro meeting:
http://www.aquaculture-europe.org/fileadmin/Aquafunc/doc/BIVALGENE-Abs.pdf
http://www.aquaculture-europe.org/fileadmin/Aquafunc/doc/BIVALGENE.pdf

Project summary :
1. Evaluation of the effect of immunostimulants on the immune response of bivalves (mussel Mytilus galloprovincialis and clam Ruditapes decussatus). Effect ofimmunomodulation on the resistance against pathogens (two vibrios associated to clam mortalities)

2. Characterization of genes involved in bivalves immune responses by two different strategies: a. Homology RT-PCR. Using primers designed in conserved sequences of cytokines b. Libraries substraction in a selected model. Trying to identify differentially expressed ESTs that are transcibed in treated animal but not in controls.

Several experimental infections were performed both in vivo and in vitro. Hemolymph samples were collected after different time points. Several immunological parameters were studied:
  • Viability
  • Phagocitosis
  • Respiratory burst activity
  • Release od nitric oxide.


List of genomic tools generated in the project :
A collection of mussel ESTs were obtained.

Publications generated in the project :

Keywords :